| ncRNA name | VASH2 shRNA |
| ncRNA Category | shRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal microvascular endothelial cell line (HRMECs) |
| Methods | transfection, immunofluorescence staining, qRT-PCR, Western blot, CCK-8 assay, flow cytometry, transwell assay, luciferase reporter assay |
| Expression pattern | associated |
| Functional description | In HRMECs, cells transfected with shRNA or miR-200b/c mimics showed a significantly reduced VASH2 expression compared with negative control group by real time-polymerase chain reaction and western-blot analysis. Inhibition of VASH2 was demonstrated to suppress cell proliferation and migration from Day 2 to Day 4. |
| PubMed ID | 28882646 |
| Year | 2017 |
| Title | Protective effect of miR-200b/c by inhibiting vasohibin-2 in human retinal microvascular endothelial cells. |
| Drug-related ncRNA | NA |
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